Poster session

Date and time

Pharmaaceuticals: 14:30-15:20 12th May, 2009.

Crystallization and Nanotechnology: 16:20-17:00 13th May, 2009.

 

Venue

CongressCenter Messe Frankfurt (CMF) Room Spektrum

 

(1)Pharmaceuticals

Nanosuspension Spray-Coating Systems for Fabrication of Microparticles with Fast-Dissolving Property of Poorly Water-Soluble Drugs
  Hideki Ichikawa, Kobe Gakuin University
  To improve the dissolution property of poorly water-soluble drugs, we have proposed a novel pharmaceutical process, Nanosuspension Spray-Coating System (NSCS), to formulate the drug nanosuspensions into a solid microparticulate unit with the layer of nano-crystalline drug-lecithin composites by the spouted bed spray coater. In this presentation, the formulation consideration on the properties of microparticles including dissolution profiles and in vivo absorption behaviors will be discussed.
   
Particle design technology with nanoparticles
  Sanshiro Nagare, Nara Machinery Co., Ltd.
  Preparation of novel materials or improvement of the properties of materials can be realised by particle design and surface modification. The Hybridization System enables fine particle coating in a dry process in a relatively short process time, e.g. 3min. The combinations of materials are infinite, therefore used in various application fields. We will also introduce the Laser Ablation System, which enables preparation of nanoparticles and direct deposition on particulate systems
   
Particle Design by Spray Drying
  Gentaro Nemoto, Ohkawara Kakohki Co., Ltd.
  For various demands about the dry product, we show effective technology example in each process (a granulation, micro encapsulation, Spray pyrolysis) of the spray dry operation. We also introduce technology example in the particle design with some development article.

 

(2)Crystallization and Nanotechnology

Production of Asymmetric Particles in a Crystallization Process using Liquid-Liquid Interfaces
  Yoshiyuki Shirakawa, Doshisha University
  A new method of crystallization using liquid/liquid interface has been applied to fabricate asymmetric particles. The crystallization process is constructed from two solvents with a little solubility each other. Solute precipitated at the interface is soluble in a solvent, but hardly in the other. The crystallization can be performed without heating and mixing, and was controlled by contact time of two liquids and concentration of the solution. Therefore, the process is simple and easy to controlling the particulate size distribution.
   
Molecular Dynamics Simulations of NaCl Cluster Formation at Solid-Liquid Interfaces
  Shinya Yamanaka, Doshisha University
  Molecular dynamics simulations of supersaturated aqueous NaCl solution including the Pt(100) or NaCl(100) crystal surfaces have been performed at an average temperature of 298K. The behavior of the NaCl cluster produced in the solution have been studied through the consideration of the water dielectric property near the crystalline surfaces for understanding the role of crystal growth on the surface.